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BMS235 Protein Biochemistry (8)

CSU Discipline Area: Biomedical Science (BIMSC)

Duration: One session

Abstract:

This subject gives an overview of protein structure and function. Experimental methods of analysis and manipulation of proteins are covered in both theory and laboratory exercises. Special reference is given to the application of proteins in biotechnology.

+ Subject Availability Modes and Locations

Session 2
Internal Wagga Wagga
Distance *Wagga Wagga

*This subject offering contains a residential school. Please view following information for further details.

Continuing students should consult the SAL for current offering details: BMS235

Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Assumed Knowledge:

BMS205 or BCM201 or BCM210

Objectives:

Upon successful completion of this subject, students should:

* be able to describe in detail the structure of proteins;
* be able to describe the forces involved in protein folding;
* be able to describe the role of proteins in ligand binding, such as in enzyme action;
* be able to describe the analytical principles behind the common methods of protein separation, purification, analysis and structural determination;
* be able to perform common experimental methods used to manipulate proteins, such as electrophoresis, centrifugation and immunochemical methods; and
* be able to describe the applications of protein engineering and proteomics in biotechnology.

Syllabus:

The subject will cover the following topics:

* basic aspects of polypeptide structure; * the three dimensional structure of proteins, including: secondary structure, alpha helix, beta sheets, beta turns; * tertiary structure, including protein motifs and domains; * quaternary structure; * proteins in solution and membranes * ligand binding and function; * experimental methods of determination of protein structure; * protein purification techniques; * protein detection and analysis techniques; * peptide synthesis techniques; and * protein engineering and proteomics.

Residential School

This subject contains a compulsory 3 day residential school.

Upon successful completion of the residential school, students should be able to perform common experimental methods used to manipulate proteins such as electrophoresis, centrifugation and immunochemical methods.

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The information contained in the 2013 CSU Handbook was accurate at the date of publication: 24 April 2013. The University reserves the right to vary the information at any time without notice.