BMS240 Human Molecular Genetics (8)
CSU Discipline Area: Biomedical Science (BIMSC)
Duration: One session
Abstract:
This subject contains basic genetic principles and mechanisms with a focus on humans and theory of molecular biology. It introduces molecular biology tools and their application to mutation detection. Ethical issues related to research, social issues, prenatal diagnosis and screening are discussed using case studies as a focus.
+ Subject Availability Modes and Locations
| Session 1 | |
|---|---|
| Internal | Orange |
| Internal | Wagga Wagga |
| Distance | Wagga Wagga |
Continuing students should consult the SAL for current offering details: BMS240
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.
Assumed Knowledge:
Objectives:
Upon successful completion of this subject, students should:
* appreciate that DNA is the genetic material in humans;
* describe the structure of DNA;
* outline how mutations result from alterations in DNA structure;
* describe the flow of genetic information from DNA through to expression as cellular constituents and structure;
* describe basic DNA mechanisms of replication, translation and transcription;
* describe how genetic information is stored in chromosomes;
* distinguish between the processes of mitosis and meiosis and their implications in terms of the inheritance of genetic material;
* distinguish different modes of inheritance - dominant/recessive; autosomal/sex-linked; non-Mendelian; multifactorial;
* understand genetic diseases, and describe the role of mutations in their aetiology and the range of human genetic diseases;
* outline the range of molecular biology tools and their application to mutation detection for diagnosis of, or screening for, genetic diseases;
* demonstrate an awareness of ethical issues related to genetics - research, social issues, prenatal diagnosis and population screening.
Syllabus:
The subject will cover the following topics:
The syllabus will cover the following topics: * DNA function and structure * Basic Genetic Mechanisms: replication, translation, transcription, DNA repair * Mutations * Chromosomes structure * Mitosis and Meiosis; Gametogenesis * Modes of inheritance: Mendelian and Non-mendelian * Population genetics * Basic molecular biology tools * Human genetic diseases * Applications: mutation detection, research, social/ethics issues, prenatal diagnosis and population screening; case studies
The information contained in the 2013 CSU Handbook was accurate at the date of publication: 24 April 2013. The University reserves the right to vary the information at any time without notice.