DOH231 Dental Biochemistry (8)
CSU Discipline Area: Dentistry and Oral Health (DENOH)
Duration: One session
Abstract:
This subject provides a foundation level understanding of the structure and function of biological macromolecules (proteins, carbohydrates, lipids, and nucleic acids) and the major metabolic and bio-energetic pathways within cells. The subject also includes study of calcium and phosphorus metabolism and an introduction to nutritional biochemistry. Oral biochemistry provides the basis for further studies by dental students in applied genetics, immunology, pathology, pharmacology-therapeutics and in clinical dental subjects where dental diseases such as caries and periodontal disease are dealt with in detail.
+ Subject Availability Modes and Locations
| Session 1 | |
|---|---|
| Internal | Orange |
Continuing students should consult the SAL for current offering details: DOH231
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.
Prerequisite(s):
Enrolment restrictions:
Restricted to Bachelor of Dental Science students only.
Objectives:
Upon successful completion of this subject, students should:
* be able to describe the chemical structures of carbohydrates, lipids, amino acids, proteins and nucleic acids, and appreciate their biological function;
* be able to describe the properties of enzymes as biological catalysts;
* be able to describe the chemical structures of nutrients in humans;
* be able to outline the major biochemical pathways used in humans, both to extract energy from the key nutrients and to synthesise new cellular components;
* be able to describe the role of energy in living cells, with particular reference to the concept of free energy and the role of ATP;
* be able to describe the role of DNA as the genetic material in humans;
* be able to demonstrate the application of common biochemical techniques to dentistry;
* be able to describe the major metabolic pathways used to synthesis ATP
* be able to demonstrate an understanding of common techniques used in the study of biochemistry
* be able to demonstrate and understanding of normal calcium and phosphorus metabolism its relationships to tooth and bone formation, mechanisms of mineralisation and its roles in relation to the maintenance of calcified dental tissue integrity
* be able to demonstrate an understanding of human nutrition in the context of biochemistry
Syllabus:
The subject will cover the following topics:
The subject will cover the following topics: # Foundations of biochemistry # The role of water in biochemistry # Amino acids, peptides and proteins # Structure and function of proteins # Enzymes # Carbohydrates # Lipids # Nucleic acids # Energy and Metabolism # Glycolysis and gluconeogenesis # Principles of metabolic regulation: glucose and glycogen # The citric acid cycle # Mitochondrial electron transport & oxidative phosphorylation # Lipid metabolism # Amino acid metabolism # Calcium and phosphorus metabolism # Biological mineralisation
The information contained in the 2013 CSU Handbook was accurate at the date of publication: 24 April 2013. The University reserves the right to vary the information at any time without notice.