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BMS207 Clinical Biochemistry 1 (8)

Abstract

This subject introduces measurement units in clinical biochemistry, types of specimens and preservatives as well as reference ranges used. The subject goes on to deal with common biochemical techniques used in most routine clinical biochemistry laboratories. Emphasis will be placed on the patho-physiological and patho-biochemical rationale for performing clinical biochemistry tests (interpretation of data) and on the analytical performance of the measurements. The latter includes but is not limited to sensitivity, linearity, specificity, quality control and quality assurance. This subject requires a sound knowledge of statistics, chemistry, anatomy, physiology and biochemistry.

+ Subject Availability Modes and Location

Session 2
InternalWagga Wagga Campus
Distance*Wagga Wagga Campus
*This subject offering contains a residential school. Please view following information for further details.
Continuing students should consult the SAL for current offering details: BMS207
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
One sessionHD/FLSchool of Biomedical Sciences

Enrolment restrictions

Prerequisite(s)
BMS130 and (BMS205 or BCM210)

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to describe the units of measurements used in clinical biochemistry;
  • be able to identify and describe (including the rationale for use) the various specimens, times of collection of specimens and preservatives used for the specimens;
  • know and be able describe importance of references values of various ions, metabolites and proteins in clinical biochemistry;
  • be able to describe the biochemical, physiological, patho-physiological and patho-biochemical rationale for routine measurements of various ions, proteins, lipids, carbohydrates, waste products and other metabolites in clinical biochemistry;
  • have the technical skills to perform measurements of the various ions, proteins, lipids, carbohydrates, waste products and other metabolites accurately and precisely;
  • be able to evaluate the different methods employed in assaying various ions, proteins, lipids, carbohydrates, waste products and other metabolites;
  • be able to describe sources of errors, quality control and quality assurance and be able to implement quality control and quality assurance on the mentioned measurements;
  • be able to describe the principles behind common and routine methods and analytical systems used in clinical biochemistry;
  • be able to describe the applications of technology, automation and information systems in clinical biochemistry.

Syllabus

The subject will cover the following topics:
  • Introduction to clinical biochemistry;
  • Units of measurement in clinical biochemistry; specimens;
  • Reference limits;
  • Errors, quality control and quality assurance concepts;
  • Technology, automation and information systems;
  • Disorders of the following: renal function; electrolytes and hydration; acid/base balance;
  • Disorders of plasma proteins;
  • Tumour markers;
  • Disorders of liver function and disorders that elevate bilirubin levels;
  • Disorders of glucose control;
  • Disorders of lipid metabolism and disorders of cardiovascular system;
  • Clinical enzymology
  • Non-protein nitrogenous wastes
  • Measurement of the levels of the constituents described, quality control assignment will be carried out. In the laboratory experiments, emphasis will be placed on appropriate standardisation/calibration and quality control procedures, execution of good and safe technical skills and on the interpretation of clinical biochemistry data.

Residential School

This subject contains a compulsory 3 day residential school. Compulsory laboratory work to develop technical skills and interpretation of clinical biochemistry data. Individual, group and class exercises will allow students to learn to work as individuals as well as to develop team work skills.

Specialised Resources

Travel to complusory Residential School

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The information contained in the 2015 CSU Handbook was accurate at the date of publication: 01 October 2015. The University reserves the right to vary the information at any time without notice.