BMS240 Human Molecular Genetics (8)


This subject will examine the broad field of genetics. It will cover standard Mendelian genetics, our modern understanding of molecular genetics, and the central dogma (DNA is transcribed to mRNA which is translated to protein). Modern disciplines of applied molecular technology (including proteomics and genomics), the genetic basis of molecular diseases, epigenetics and the genetics of cancer will also be examined..

+ Subject Availability Modes and Location

Session 1
InternalOrange Campus
InternalWagga Wagga Campus
DistanceWagga Wagga Campus
Continuing students should consult the SAL for current offering details: BMS240
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
One sessionHD/FLSchool of Biomedical Sciences

Assumed Knowledge

CHM107 and BMS130 or BMS128

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to distinguish between the processes of mitosis and meiosis and their implications in terms of the inheritance of genetic material;
  • be able to describe Mendelian inheritance patterns
  • be able to describe and differentiate between different modes of inheritance
  • be able to describe that DNA is the genetic material in humans;
  • be able to describe how genetic information is stored in chromosomes and how chromosomes can be mutated
  • be able to describe the structure of DNA
  • be able to describe and apply the flow of genetic information from DNA through to expression as cellular constituents and structure
  • be able to describe basic DNA mechanisms of replication, translation and transcription
  • be able to outline how mutations result from alterations in DNA structure
  • be able to describe standard molecular technologies and the newer technologies of proteomics and genomics
  • be able to describe the role of epigenetics in human inheritance
  • be able to describe how genetics plays a role in human disease
  • be able to describe how mutations play a role in several human genetic diseases (with a focus on cancer)


The subject will cover the following topics:
  • Chromosomes and cellular reproduction
  • Basic principles of heredity
  • Sex determination and sex linked characteristics
  • Extensions and modifications of basic principles
  • Pedigree analysis, applications, genetic testing and ethics
  • Linkage, recombination and eukaryotic gene mapping
  • Chromosome variation
  • DNA: The chemical nature of the gene
  • Chromosome structure and DNA replication
  • Transcription
  • RNA molecules and RNA processing
  • The genetic code and translation
  • Gene mutations and DNA repair
  • Molecular genetic analysis and genomics/proteomics
  • Epigenetics and cancer genetics


The information contained in the 2016 CSU Handbook was accurate at the date of publication: 06 September 2016. The University reserves the right to vary the information at any time without notice.