BMS291 Pathophysiology and Pharmacology 1 (8)


This subject explores pathophysiological processes contributing to disease. This subject focuses on pathophysiological processes associated with musculoskeletal, cardiovascular and respiratory dysfunction. Relevant pharmacology is integrated throughout.

+ Subject Availability Modes and Location

Session 1
InternalAlbury-Wodonga Campus
InternalBathurst Campus
InternalDubbo Campus
InternalOrange Campus
InternalPort Macquarie
InternalWagga Wagga Campus
DistanceOrange Campus
Session 2
DistanceOrange Campus
Continuing students should consult the SAL for current offering details: BMS291
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
One sessionHD/FLSchool of Biomedical Sciences

Enrolment restrictions

Prerequisite(s)Incompatible subject(s)
BMS192 or (BMS130 and MCR101)BMS101 BMS102 BMS121 BMS122 BMS221 BMS222 BMS231 BMS232

Learning Outcomes

Upon successful completion of this subject, students should:
be able to:
* define common pathophysiological and pharmacological terms;
* describe characteristics and origin of different types of cellular injury;
* demonstrate an understanding of cellular adaptation to injury;
* identify the interaction and relative contribution genetic and environmental factors have on health breakdown;
* describe the characteristics of cancerous cells;
* describe the four pharmacokinetic processes (absorption, distribution, metabolism and elimination);
* outline key pharmacodynamic principles (eg agonist and antagonists, receptor-drug interactions);
* describe the involvement of microorganisms in disease;
* name and describe the actions of the major classes of antimicrobial drugs;
* describe the consequences of alterations in fluids, electrolytes and acid-base balance;
* outline the major haematological pathologies and malignancies;
* describe the pathogenesis of major cardiovascular system dysfunction;
* describe the aetiology and manifestations of shock;
* outline the primary pharmacological interventions used in the treatment of cardiovascular disease;
* describe the pathogenesis of common respiratory dysfunctions;
* describe use of pharmacological agents in the treatment and management of respiratory pathophysiological states;
* describe the major types of musculoskeletal pathology including both mechanical and physiological injuries;
* demonstrate understanding of the origin and main theories of pain; and
* explain the pharmacological treatment of inflammation and pain.


The subject will cover the following topics:
* Cell injury, adaptation and death
* Pharmacokinetics and pharmacodynamics

* Fluid, electrolyte and acid-base imbalances
* Pain and analgesic agents
* Inflammation and anti-inflammatory agents
* Infectious disease and antimicrobial agents
* Neoplastic disorders and antineoplastic agents

* Cardiovascular dysfunction (coagulopathy, hypertension, atherosclerosis, dysrhythmias, pump failure) and associated pharmacology
* Respiratory dysfunction (asthma, chronic airways limitation, hypoventilation, pulmonary hypertension) and associated pharmacology
* Musculoskeletal dysfunction (arthritis, osteoporosis, metabolic disorders, muscular dystrophy) and associated pharmacology


The information contained in the 2016 CSU Handbook was accurate at the date of publication: 06 September 2016. The University reserves the right to vary the information at any time without notice.