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BMS302 Clinical Biochemistry 2 (8)

Abstract

The subject covers monogenic diseases, clinical endocrinology, endocrine aspects of dysfunction in calcium, phosphate and magnesium control, immunochemical techniques, toxicology and drug monitoring. Clinical biochemistry biochemistry methods of investigating endocrine disorders, drugs and monogenetic defects are covered. It is therefore important that a student should have a sound knowledge of statistics, chemistry, anatomy, physiology, biochemistry.

+ Subject Availability Modes and Location

Session 1
InternalWagga Wagga Campus
Distance*Wagga Wagga Campus
*This subject offering contains a residential school. Please view following information for further details.
Continuing students should consult the SAL for current offering details: BMS302
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
One sessionHD/FLSchool of Biomedical Sciences

Enrolment restrictions

Prerequisite(s)Incompatible subject(s)
BMS207BMS330

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to describe the steps involved in setting up an immunoassay for routine measurements in a clinical biochemistry;
  • be able to describe the different types of immunoassays and their merits and be able to describe the theoretical principle (s) behind each type;
  • be competent in measuring levels of constituents (e.g. hormones and drugs) using immunochemical or other methods in use and be able to describe the theoretical principle (s) behind each type;
  • be able to describe how endocrine diseases arise;
  • be able to describe the patho-biochemical and patho-physiological rationale for evaluation of endocrine function in health and disease;
  • be able to describe the clinical biochemistry techniques used in the identification, screening and management of endocrine diseases;
  • be able to describe how monogenetic metabolic defects arise including but not limited to cystic fibrosis, phenylketonuria, Huntington disease, Gauchers disease;
  • be able to describe the clinical biochemistry and molecular biology techniques used in identification, screening and management of monogenetic diseases;
  • be competent in measuring levels of metabolites in biological fluids or tissues in identification, screening and management of monogenetic diseases and be able to describe the theoretical principle (s) behind each type;
  • be able to outline pharmacokinetic principles and their application to clinical biochemistry monitoring of therapeutic drugs;
  • be able to identify and describe the techniques for identification and/or quantitative analysis of drugs and be able to describe the principle (s) behind each type.

Syllabus

The subject will cover the following topics:
  • Immunochemical techniques in clinical biochemistry
  • Human monogenetic disorders
  • Endocrine diseases
  • Endocrine aspects leading to changes in levels of calcium, phosphate and magnesium in blood
  • Drug analysis
  • Techniques (theory and practical) e.g. immunochemical, chromatographic, chemical used in analysis of hormones, ions, drugs and metabolites associated with monogenetic diseases;

Residential School

This subject contains a compulsory 3 day residential school. Compulsory laboratory work to develop technical skills and interpretation of clinical biochemistry data. Individual, group and class exercises will be carried to allow students to learn to work as individuals as well as to develop team work skills.

Specialised Resources

Travel to compulsory Residential School

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The information contained in the 2016 CSU Handbook was accurate at the date of publication: 06 September 2016. The University reserves the right to vary the information at any time without notice.