PHM231 Pharmaceutics 2 (16)


This subject concentrates on the physicochemical properties of drugs and their effect on the design of dose forms. It examines in greater depth the formulation of solutions, suspensions, emulsions, powders, tablets, capsules, parenteral and ophthalmic products, topical and transdermal products, suppositories and pessaries as well as pulmonary aerosols. In addition, several topics address some fundamental pharmaceutical science issues, including the roles of polymers in formulation, packaging materials and technologies, drug dissolution and diffusion and product stability. Accreditation requirements established by the Australian Pharmacy Council and enunciated in the National Competency Standards Framework for Pharmacists in Australia (2010) inform the content of this subject. Domain 5 of the standards (Prepare Pharmaceutical Products) is key; in particular standards 5.1 (Consider product requirements) and 5.2 (Prepare non-sterile drug products). In addition, Domain 7 (Standard 7.1, Contribute to therapeutic decision making) is important, since knowledge of how dose-forms work is important to advising other health-care providers and also counselling the patient.

+ Subject Availability Modes and Location

Session 1
InternalOrange Campus
InternalWagga Wagga Campus
Session 2
InternalOrange Campus
InternalWagga Wagga Campus
Continuing students should consult the SAL for current offering details: PHM231
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
Two sessionsHD/FLSchool of Biomedical Sciences

Assumed Knowledge

CHM107 and PHM131

Enrolment restrictions

Incompatible subject(s)
PHM211 PHM311

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to demonstrate skills in and an understanding of the procedures necessary for consistent formulation;
  • be able to recognise and explain the importance of due care and diligence in formulation;
  • be able to demonstrate an appreciation for the need for a range of formulations;
  • be able to identify and explain the critical factors determining both the optimal and preferential use of different dose forms;
  • be able to identify and explain the critical factors for appropriate storage of drug products; and
  • be able to demonstrate an appreciation of how the physicochemical properties of drugs influence the selected dose form and formulation.


The subject will cover the following topics:
  • some physicochemical properties of drugs and their effect on development of dose forms
  • the application of polymers in pharmacy
  • drug dissolution and diffusion
  • aspects of chemical drug stability and the impact of packaging
  • physicochemical properties of pharmaceutical vehicles such as solutions, suspensions and both fluid and semisolid emulsions
  • properties and formulation of parenteral, ophthalmic, nasal and otic products
  • properties and formulation of transdermal products
  • properties and formulation of pulmonary aerosols
  • properties and formulation of pharmaceutical solids, tablets and capsules
  • properties and formulation of suppositories and pessaries
  • fundamentals of veterinary dose-form development
  • novel and targeted drug delivery systems and currently employed controlled release preparations


The information contained in the 2016 CSU Handbook was accurate at the date of publication: 06 September 2016. The University reserves the right to vary the information at any time without notice.