DOH233 Pathological Basis of Human Disease (8)

Students will gain a foundation level understanding of the biochemical, cellular and tissue responses that can arise as a consequence of injury to cells, tissues and body organ systems. This understanding will be developed in the context of the aetiology and pathogenesis of basic pathological processes. This includes inflammation and sequelae, immunological reactivity, hypertrophy and hyperplasia, healing and neoplasia. The students will also gain an understanding of the pathogenesis and clinical, macroscopic, and microscopic features of common and important human diseases relevant to dental practice



Session 2 (60)
On Campus
Orange Campus

Continuing students should consult the SAL for current offering details: DOH233. Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject Information

Grading System



One session


School of Dentistry and Health Sciences

Enrolment Restrictions

Restricted to students enrolled in the Bachelor of Dental Science course.


BMS130 and PSY111 and CHM102 and DOH133 and DOH114 and DOH124

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to use discipline-specific terminology to describe, identify, explain, and compare the clinical, macroscopic, and microscopic features of disease processes;
  • be able to identify, describe, discuss and compare the clinical, macroscopic, and microscopic features of disease-related processes including but not limited to; inflammation, immune hypersensitivities, hypertrophy, hyperplasia, hard and soft tissue wound healing and neoplasia;
  • be able to apply knowledge of the pathological basis of disease processes to compare and explain clinical, macroscopic, and microscopic features of common dental and medical diseases; and
  • be able to demonstrate an understanding of evidence-based practice through the critical appraisal of the current knowledge of disease processes.
  • be able to demonstrate an understanding of the nature of and host and injury variables that may affect the expression of disease


This subject will cover the following topics:
  • Introduction to pathology;
  • Responses to cellular injury;
  • Ischaemia, infarction, and shock;
  • Healing and repair;
  • Immunopathology;
  • Inflammation;
  • Pathology of infectious disease;
  • Neoplasia;
  • Genetic and developmental disorders;
  • Cardiovascular and blood disorders (haemostatic disorders, hypertension, coronary heart disease, heart failure);
  • Respiratory disorders (asthma, COPD, obstructive sleep apnoea);
  • Endocrine disorders (diabetes, thyroid disorders, adrenal disorders, bone and calcium metabolism disorders); and
  • Neurological disorders (stroke, epilepsy, neurodegenerative disorders).


For further information about courses and subjects outlined in the CSU handbook please contact:

Current students

Future students

The information contained in the CSU Handbook was accurate at the date of publication: May 2019. The University reserves the right to vary the information at any time without notice.