This subject covers the application of principles and methods of chemical analysis of drugs. Major areas include, chemical analysis, diagnostic applications and receptor structure and drug binding. It covers the medicinal chemistry of a wide range of current therapeutic agents and provides the basis for an understanding of the principles and techniques for development of future drugs.
HD/FL
Two sessions
School of Biomedical Sciences
CHM219
PHM322, PHM323
* rational structurally-based and mechanism-based approaches to drug design;
* drug structure, reactivity and metabolism;
* introduction to the basis of and applications for infra-red, ultra-violet, nuclear magnetic resonance spectroscopy, and mass spectrometry;
* sampling techniques and analytical testing; spectroscopy and chromatography;
* structure and bonding in biological macromolecules;
* the use of enzyme inhibitors as drugs with focus on NSAIDS and antihypertensives;
* the medicinal chemistry of a broad range of therapeutic agents.
* pharmacognosy: methods of extraction, preparation and analysis of drugs from natural sources;
* selected herbal remedies;
* structure-activity relationships and molecular conformation in CNS active drugs with special reference to opioids, antidepressants and anticonvulsants;
* structure and function of selected steroids;
* structure-activity relationships and mechanisms of antimicrobial agents;
* antineoplastic drugs.
The following table summarises the assessment tasks for the online offering of PHM320 in Session 1 2019. Please note this is a guide only. Assessment tasks are regularly updated and can also differ to suit the mode of study (online or on campus).
The information contained in the CSU Handbook was accurate at the date of publication: October 2020. The University reserves the right to vary the information at any time without notice.