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BMS235 Protein Biochemistry (8)

Abstract

This subject gives an overview of protein structure and function. Experimental methods of analysis and manipulation of proteins are covered in both theory and laboratory exercises. Special reference is given to the application of proteins in biotechnology.

+ Subject Availability Modes and Location

Session 2
Online*Wagga Wagga Campus
On CampusWagga Wagga Campus
*This subject offering contains a residential school. Please view following information for further details.
Continuing students should consult the SAL for current offering details: BMS235
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
One sessionHD/FLSchool of Biomedical Sciences

Assumed Knowledge

This subject has no prerequisites although successful completion of BCM210 or equivalent is assumed.

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to describe in detail the structure of proteins;
  • be able to describe the forces involved in protein folding;
  • be able to describe the role of proteins in ligand binding, such as in enzyme action;
  • be able to describe the analytical principles behind the common methods of protein separation, purification, analysis and structural determination;
  • be able to perform common experimental methods used to manipulate proteins, such as electrophoresis, centrifugation and immunochemical methods; and
  • be able to describe functional assays used to study proteins;
  • be able to describe the applications of protein engineering

Syllabus

The subject will cover the following topics:
  • basic aspects of polypeptide structure;
  • the three dimensional structure of proteins, including: secondary structure, alpha helix, beta sheets, and beta turns; tertiary structure, including protein motifs and domains; quaternary structure;
  • ligand binding and function;
  • methods of determination of protein structure;
  • protein expression and purification techniques;
  • protein detection and analysis techniques;
  • protein engineering

Residential School

This subject contains a compulsory 3 day residential school. Upon successful completion of the residential school, students will be able to perform common techniques used to manipulate proteins such as electrophoresis, centrifugation and immunochemical methods. 

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The information contained in the 2018 CSU Handbook was accurate at the date of publication: 24 November 2017. The University reserves the right to vary the information at any time without notice.