BMS302 Clinical Biochemistry 2 (8)

This subject is a continuation of Clinical Biochemistry 1 and covers techniques in measurements of endogenous and exogenous metabolites found in low levels in biological specimens. These metabolites include, but are not limited to, hormones and drugs that are used in therapy and/or that are abused. Techniques inclusive of the various types of immunoassays as well as mass spectrometry are therefore covered. Monogenic diseases are learnt with emphasis on cystic fibrosis and phenylketonuria. Clinical endocrinology is studied and various endocrine disorders are emphasised to illustrate development of endocrine diseases and the importance of clinical biochemistry in diagnosis and management of endocrine disorders. On completion of this subject, a student is equipped with theoretical and technical skills for clinical biochemical investigation of endocrine disorders, monogenic diseases and drugs. Such knowledge is useful for example in further studies in this discipline and also other disciplines such as forensic sciences, dentistry, medicine and veterinary as well as animal sciences, routine and specialist pathology, research and in industry that develops and/or supplies diagnostic technology and consumables.

Subject availability
* Offering has a residential school. Please view following information for further details.
Session 1 (30)
Online *
Wagga Wagga Campus
Continuing students should consult the SAL for current offering details. Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.
Subject Information
Grading System
One session
School of Biomedical Sciences
Incompatable Subjects
Learning Outcomes
Upon successful completion of this subject, students should:
  • be able to describe and evaluate the various techniques (including but not limited to recognition techniques and mass spectrometry) utilised in measurement of endogenous metabolites and drugs found in low concentrations in biological fluids/tissues in various diseases
  • be able to measure competently the levels of drugs and constituents associated with endocrine and monogenic diseases
  • be able to describe how endocrine diseases and monogenic diseases (e.g. cystic fibrosis and phenylketonuria) arise and to describe and evaluate the patho-biochemical/patho-physiological rationale for screening, diagnosis and management of these diseases
  • be able to describe and analyse the rationale for measuring drugs and describe pharmacokinetic principles and their importance to clinical biochemistry
  • be able to describe and evaluate toxicological exposure involving chemicals and metals
  • be able to work independently and collaboratively in measurement of analyses and to write a scientific report on experimental findings and data interpretation
The subject will cover the following topics:
  • Human monogenic disorders
  • Endocrine diseases
  • Endocrine control of calcium, phosphate and magnesium levels and changes to this control in disease
  • Drugs
  • Techniques (theory and practical) including, but not limited to chemical, immunoassays, chromatographic and mass spectrometry used in investigations and management of endocrine and monogenic diseases and in measurement of ions and drugs
Residential School
This subject contains a 3 day Compulsory Residential School.

Compulsory laboratory work to develop technical skills and interpretation of clinical biochemistry data. Individual, group and class exercises will be carried out, to allow students to learn to work as individuals as well as develop team work skills.

Special Resources

Travel to and accommodation is required for distance education students attending the compulsory residential school at a CSU campus.

All students are required to have a lab coat, safety glasses and covered footwear for lab based practicals.

Current Students

For any enquiries about subject selection or course structure you will need to contact your Course Director. You can find the name and contact details for your Course Director in your offer letter or contact your School office.

Prospective Students

For further information about Charles Sturt University, or this course offering, please contact info.csu on 1800 334 733 (free call within Australia) or enquire online.

The information contained in the 2017 CSU Handbook was accurate at the date of publication: June 2018. The University reserves the right to vary the information at any time without notice.