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BMS308 Immunology (8)

Abstract

This subject considers the immune response, antibodies and the complement systems and a treatment of experimental immunological techniques. The two clinical application modules consider pathology of immunodeficiency, autoimmunity and hypersensitivity and laboratory evaluation of immune function disorders. This subject has a compulsory 4 day residential school.

+ Subject Availability Modes and Location

Session 1
Online*Wagga Wagga Campus
On CampusWagga Wagga Campus
*This subject offering contains a residential school. Please view following information for further details.
Continuing students should consult the SAL for current offering details: BMS308
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
One sessionHD/FLSchool of Biomedical Sciences

Assumed Knowledge

Assumed knowledge for BMS308 Immunology includes:
  • proteins:  their function and hierarchy of structure,  carbohydrates: their occurrence and structural roles in vertebrates;
  • nucleic acids: structure and function including recombination, gene expression and vertebrate inheritance pattern as covered in BMS241 or other molecular biology subject;
  • the host  pathogen interactions as covered in Introductory Microbiology (BMS115 or MCR101)
  • Other as determined by Course Director

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to explain the structure and properties of the tissues, cells and molecules involved in immune responses;
  • be able to explain the mechanisms of immune responses and of anti-microbial defences;
  • be able to critically evaluate the range of immunological techniques capable of being employed in modern biomedical science;
  • be able to perform a range of immunological techniques;
  • be able to explain the pathology of the immune system with particular reference to immunodeficiency diseases, hypersensitivity reactions, infectious diseases and autoimmune diseases; and
  • be able to explain the theory behind the laboratory techniques used to evaluate diseases of the immune system and be able to perform these tests.

Syllabus

The subject will cover the following topics:
  • Immunological concepts
  • Introduction to Immunology, including anatomy and ontogeny of the immune system
  • Cells involved in the immune system: lymphocytes, macrophages, mast cells and other accessory and effector cells; their ontogeny, occurrence and the generation of T and B cell antigen recognition diversity
  • Molecules involved in the immune response with special reference to the structure and function of antigens, antibodies and cell receptors; antigen recognition and antibody function
  • Innate immunity
  • The complement system
  • Specific acquired immunity - antibodies and effector cell function in cell-mediated immunity
  • Cellular interaction and T cell and B cell activation in adaptive immunity
  • Cytokines in the ontogeny of immune cells and in the induction and expression phases of immunity
  • Experimental Tools of Immunology
  • Immunoprecipitation, including immunoelectrophoresis
  • Immunoassays, with special reference to ELISA, particle agglutination, haemagglutination, neutralisation and complement-fixation techniques
  • Immunofluorescence techniques
  • Clinical Immunology
  • The pathology of the following immune disorders:
  • Immunodeficiency diseases
  • Hypersensitivities I-IV
  • Autoimmune diseases
  • Laboratory evaluation of immune system dysfunction
  • Hypersensitivities: their laboratory evaluation
  • Autoimmune Diseases: their laboratory evaluation
  • Isolation, identification and enumeration of cells of the immune system in the evaluation of immunodeficiency diseases.

Residential School

This subject contains a compulsory 4 day residential school. Students to obtain a practical understanding of immunology and to learn to perform key laboratory techniques used to evaluate diseases of the immune system and perform important immunological assays

Specialised Resources

This subject has a compulsory 4 day residential school
 

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The information contained in the 2018 CSU Handbook was accurate at the date of publication: 24 November 2017. The University reserves the right to vary the information at any time without notice.