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Dr Ata Rehman
BSc, MSc, PhD (London)
Position Molecular Biologist
Adjunt Senior Lecturer
Location NSW DPI, Wagga Wagga
Phone 02 6938 1902
Fax 02 6938 1809
Email ata.rehman@dpi.nsw.gov.au
Career Brief
Completed PhD studies from King's College, University of London, UK in 1991. The work included purification of two types of laccases (1&11) and cloning of laccase-1 gene from the root rot fungus Armillaria mellea .
The postdoctoral research included, Agrobacterium mediated transformation of pasture legume Medicago truncatula; construction of different gene cassettes and their biolistic and electroporation mediated, delivery in cereals (wheat, barley & rice) and Isolation, cloning and transformation of the Glycerol phosphate dehydrogenase genes (GPD1 & 2) in the wine yeast, to produce low alcohol wines with improved sweetness and palate.
Current and past research and supervisory activities includes development and implementation of DNA and protein markers for improvement of cereals crops such as barley, wheat, rice and canola; genetic identification of Australian olives cultivars and olive oils using molecular markers; supervision of a number of Masters and PhD students.
Research and Teaching
Research
- Genetic linkage mapping, QTL analysis and identification of trait(s) linked to drought and black-leg resistance in canola.
- Characterisation of Wattle Seed (Acacia victoriae) Protease Inhibitors and the Functional Properties of wattle seed extract.
- The pharmacological mechanism of action of biologically active molecules, from plants and animal milk, on DNA as an anticancer target.
- Characterisation of Spelt ( Triticum aestivum ssp. spelta L) and Aegilops.tauschii germplasm for the polymorphism on the glutenin genes to identify novel glutenin alleles.
- Characterization of genetic diversity in Australian olive germplasm to develop higher yielding varieties with good quality health attributes.
- Identification of novel therapeutic biophenols and inhibitors of proteolytic enzymes and to elucidate their molecular mechanism of action in the prevention of cancer, cardiovascular and inflammatory diseases and HIV AIDS.
Teaching
Currently supervising both Masters and PhD students on following topics:
• The pharmacological mechanism of action of olive biophenols at the DNA level: How can dietary antioxidants fight cancer?.
• Characterization of protease inhibitors in Australian Wattle seed ( Acacia victoriae Bentham) and the functional properties of seed extract.
• Non-cow milk constituents and their health-functional properties.
Interests
Characterization of genetic diversity in Australian olive genotypes to develop higher yielding varieties with good quality health attributes.
Identification of novel therapeutic b iophenols and inhibitors of proteolytic enzymes and to elucidate their molecular mechanism of action in the prevention of cancer, cardiovascular and inflammatory diseases and HIV AIDS.
Selected Publications
Hassan K. Obied, Izabela Konczak, Paul D. Prenzler (a) , Ata-u-Rehman (c) and Kevin Robards (2009). Chemistry and Bioactivity of Olive Biophenols in some Antioxidant and Anti-proliferative in vitro Bioassays . Chem. Res. Toxicol , 22, 227–234.
Chan, S., Agboola, S., Rehman, A (2009). Application of rennet-like proteases from Australian cardoon (Cynara cardunculus L.) in cheese making from ultrafiltered bovine milk. LWT - Food Science and Technology 42, 1352–1359.
Kah Y. Ee Ata-ur-Rehman , Jian Zhao and Samson Agboola (2009). Purification and Characterization of a Kunitz-Type Trypsin Inhibitor from Acacia victoriae Bentham Seeds . J. Agric. Food Chem. 2009, 57, 7022–7029.
A. Rehman , N.Evans, M.C. Gianibelli, P. Martin and R.J.Rose (2008). Allelic variation of high and low molecular weight Glutenin subunits at Glu-D t in Triticum tauschii as a source of improving bread wheat quality. Australian Journal of Agriculture Research Volume 59, No 5, p 399-405.
Ee, K.Y., Zhao, J, Rehman, A. and Agboola, S (2008). Characterisation of trypsin and a-chymotrypsin inhibitors in Australian wattle seed ( Acacia victoriae Bentham). Food Chemistry, 107, 337-343.