BMS346 Genomics, Proteomics and Bioinformatics (8)

Genomics, proteomics and bioinformatics are the cornerstones of the so-called 'Omics technologies that are routinely applied in medical research and throughout the drug-development process. In recent years genomic and proteomic technologies, combined with bioinformatics, and rapid progress in high throughput technologies, have made it possible to study gene regulation and protein function in high throughput. In contrast to studies of single genes or single proteins, genomic and proteomic methods simultaneously investigate large numbers of genes or proteins in one single experiment. This capstone subject will focus on the historical development of these technologies to provide a platform from which the key applications, techniques and recent advances in these fields can be appreciated.


Session 2 (60)
Wagga Wagga Campus

Continuing students should consult the SAL for current offering details: BMS346. Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject Information

Grading System



One session


School of Biomedical Sciences

Assumed Knowledge

Second year undergraduate biochemistry (particularly protein biochemistry), genetics, biotechnology and molecular cell biology.

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to describe the development of Omics technologies, with emphasis on genomics and proteomics;
  • Be able to synthesise information to discuss the key technological developments that enabled modern genomic and proteomic studies;
  • be able to describe advanced genomics and proteomics technologies and the ways in which their data are stored;
  • be able to use bioinformatics techniques to query examples of genomic and proteomic databases to analyse cell biology;
  • be able to describe the different types of genome variation and their relationship to human diseases;
  • be able to discuss how biological systems information relating to genes, proteins and cellular structures can be used to model living cells, and even to create new synthetic cells.


This subject will cover the following topics:
  • A historical perspective on the development of omics technologies
  • Genomics: an introduction to genomics, databases and sequence comparison techniques, genes and the genome, principles and applications of DNA microarray technology, transcriptional profiling, micro-array applications, SNP, QTL and genotyping, modern genome sequencing, genome variation and phylogeny, biomes, and transcriptomics.
  • Proteomics: early origins of proteomics, gel-based proteome profiling, the rise of different mass spectrometry methods, modern high throughput mass spectrometry, protein data bases
  • Bioinformatics: mining data bases for genetic, transcriptional and protein-based information, including an introduction to web based tools such as NCBI and UNIPROT.
  • Systems biology: integrated biological analysis involving multiple omics inputs and bioinformatic processes to predictively model biological systems in silico

Indicative Assessment

The following table summarises the assessment tasks for the online offering of BMS346 in Session 2 2020. Please note this is a guide only. Assessment tasks are regularly updated and can also differ to suit the mode of study (online or on campus).

Item Number
Value %
Assignment 1 - gene variation problem set
Assignment 2 - databases problem set
Assignment 3 - phylogenetics problem set
Assignment 4 -transcriptomics problem set
Assignment 5 -research paper

The information contained in the CSU Handbook was accurate at the date of publication: May 2021. The University reserves the right to vary the information at any time without notice.