PHM341 Pharmacokinetics (8)

This subject is based on an understanding of pharmacology, pharmaceutical chemistry and human physiology, examines pharmaceutical, pharmacokinetic and pharmacodynamic principles pertinent to drug action to attain therapeutic objectives. This subject also looks at typical pharmacokinetics and in special cases such as disease states, pregnancy, lactation, paediatrics and geriatrics, taking into account issues of patient compliance.


Session 1 (30)
On Campus
Orange Campus

Continuing students should consult the SAL for current offering details: PHM341. Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject Information

Grading System



One session


School of Biomedical Sciences

Assumed Knowledge

CHM219, PHM231 and the mathematics of exponential/logarithmic functions.

Learning Outcomes

Upon successful completion of this subject, students should:
  • be able to understand the biological and pharmaceutical factors influencing the absorption, distribution, metabolism and elimination of drugs;
  • use calculations to demonstrate the importance of pharmacokinetics in determining the bioavailability and disposition of drugs;
  • demonstrate an appreciation the differences in individuals which influence drug action (pharmacogenetics and pharmacogenomics);
  • be able to explain the significance of client/patient compliance;
  • be able to demonstrate an understanding of the mechanisms of drug-drug/drug-food interactions.
  • be able to outline a number of pharmacokinetic models, including: single compartment, multiple compartment and non-linear pharmacokinetics;


This subject will cover the following topics:
  • absorption, distribution, metabolism and elimination of drugs;
  • primary pharmacokinetic parameters including: apparent volume of distribution, clearance, and rate constants associated with drug absorption and elimination;
  • IV and extravascular administration of drugs;
  • concepts of bioequivalence and bioavailability;
  • therapeutic drug monitoring;
  • multiple dosage regimes;
  • linear and non-linear pharmacokinetics;
  • individualised pharmacokinetics e.g. special cases such as disease states, pregnancy, lactation, paediatrics and geriatrics;
  • principles of drug interactions;

Indicative Assessment

The following table summarises the assessment tasks for the online offering of PHM341 in Session 1 2020. Please note this is a guide only. Assessment tasks are regularly updated and can also differ to suit the mode of study (online or on campus).

Item Number
Value %
Quiz 1
Quiz 2
Mid-session exam
Final exam

The information contained in the CSU Handbook was accurate at the date of publication: May 2021. The University reserves the right to vary the information at any time without notice.