PHM412 Radiopharmacy (8)

This subject provides a detailed education in the practice and procedure of the radiopharmacy. Specifically, the subject provides students with an understanding of radiation safety, safe radiopharmacy practice, radionuclide production, dose calculation and dispensing and the chemical, physical and biological properties of a variety of radiopharmaceuticals. Further, this subject aims to provide students with practical skill development in radiation safety, dose dispensing, radiopharmacy quality control, radiopharmaceutical reconstitution and blood cell labelling. This subject also provides education in radiopharmacy practice with emphasis on receipt, storage and handling of radiopharmaceuticals; reactor / cyclotron produced radiopharmaceuticals and the physiological pathways of various radiopharmaceuticals. The subject aims to provide deeper learning and understanding of the principles and practice of Nuclear Pharmacy.


Session 1 (30)
On Campus
Port Macquarie Campus
Wagga Wagga Campus
Wagga Wagga Campus

Continuing students should consult the SAL for current offering details: PHM412. Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject Information

Grading System



One session


School of Dentistry and Health Sciences

Learning Outcomes

Upon successful completion of this subject, students should:
  • Be able to understand and correctly utilise key terms and concepts;
  • Be able to describe the physiological pathways of the radiopharmaceuticals and mechanisms of localisation of each;
  • Be able to explain at a broad level paediatric considerations in radiopharmacy;
  • Be able to describe and be able to conduct research into new and emerging tracers;
  • Be able to apply critical, analytical, and evaluative skills at a developing level in a range of contexts including clinical problem solving, research and empirical practice, and academic and professional discourse;
  • Be able to describe and explain the principles of radiopharmacy operation including, but not limited to, receipt, storage and disposal of radionuclides, radiation safety, legislative and regulatory requirements, radionuclide production, radiopharmaceutical reconstitution, and dose dispensing;
  • Be able to demonstrate and apply those characteristics that enhance autonomous and life long learning;
  • Be able to identify and deploy effective communication skills in a variety of settings using a variety of media.


This subject will cover the following topics:

The syllabus will cover the following topics:
" Terminology
" Receipt, handling, storage and waste disposal of sealed and unsealed sources
" Specific activity, calibration and delivery time and time zones
" Radionuclide generators
" Reconstitution of cold kits
" Quality assurance of radiopharmaceutical kits
" Efficient calculation of a dose to be dispensed
" Method of dose dispensing for intravenous injection
" Radionuclide production
" Radiopharmaceutical properties and mechanisms of localisation
" Radiopharmaceutical chemistry
" Radiopharmacokinetics
" Receptors and peptides
" Therapeutic applications
" Radiation protection, safety, monitoring and decontamination
" Radiopharmacy design
" Exercises in decontamination and radioactive monitoring
" Labelling procedures for red blood cells
" Principles of ALARA in the Hot Lab
" Research and development

Indicative Assessment

The following table summarises the assessment tasks for the online offering of PHM412 in Session 1 2020. Please note this is a guide only. Assessment tasks are regularly updated and can also differ to suit the mode of study (online or on campus).

Item Number
Value %
Pre-clinical practicals
Calculation exam

The information contained in the CSU Handbook was accurate at the date of publication: May 2021. The University reserves the right to vary the information at any time without notice.