PHM341 Pharmacokinetics (8)
AbstractThis subject is based on an understanding of pharmacology, pharmaceutical chemistry and human physiology, examines pharmaceutical, pharmacokinetic and pharmacodynamic principles pertinent to drug action to attain therapeutic objectives. This subject also looks at typical pharmacokinetics and in special cases such as disease states, pregnancy, lactation, paediatrics and geriatrics, taking into account issues of patient compliance. |
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+ Subject Availability Modes and Location
Session 1 | On Campus | Orange Campus | On Campus | Wagga Wagga Campus |
Continuing students should consult the SAL for current offering details: PHM341
Where differences exist between the Handbook and the SAL, the SAL should be taken as containing the correct subject offering details.
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Subject informationDuration | Grading System | School: |
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One session | HD/FL | School of Biomedical Sciences |
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Assumed Knowledge
CHM219, PHM231 and the mathematics of exponential/logarithmic functions.
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Learning OutcomesUpon successful completion of this subject, students should:
- be able to understand the biological and pharmaceutical factors influencing the absorption, distribution, metabolism and elimination of drugs;
- use calculations to demonstrate the importance of pharmacokinetics in determining the bioavailability and disposition of drugs;
- demonstrate an appreciation the differences in individuals which influence drug action (pharmacogenetics and pharmacogenomics);
- be able to explain the significance of client/patient compliance;
- be able to demonstrate an understanding of the mechanisms of drug-drug/drug-food interactions.
- be able to outline a number of pharmacokinetic models, including: single compartment, multiple compartment and non-linear pharmacokinetics;
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SyllabusThe subject will cover the following topics:
- absorption, distribution, metabolism and elimination of drugs;
- primary pharmacokinetic parameters including: apparent volume of distribution, clearance, and rate constants associated with drug absorption and elimination;
- IV and extravascular administration of drugs;
- concepts of bioequivalence and bioavailability;
- therapeutic drug monitoring;
- multiple dosage regimes;
- linear and non-linear pharmacokinetics;
- individualised pharmacokinetics e.g. special cases such as disease states, pregnancy, lactation, paediatrics and geriatrics;
- principles of drug interactions;
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The information contained in the 2017 CSU Handbook was accurate at the date of publication: 25 August 2017. The University reserves the right to vary the information at any time without notice.