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DOH212 Oral Health Pathophysiology & Pharmacology 1 (12)

Abstract

This subject explores pathophysiological processes contributing to systemic disease and introduces the topic of oral diseases. The systemic disease component of the subject focuses on pathophysiological processes associated with the musculoskeletal, cardiovascular and respiratory systems. Pharmacology relevant to the management of the diseases and topics covered is integrated throughout. Students will complete this subject with an understanding of diseases of these systems and of the oral implications of disease in these systems in the context of oral health practice. Students will also begin study of primary pathologies occuring in the orofacial region.

+ Subject Availability Modes and Location

Continuing students should consult the SAL for current offering details prior to contacting their course coordinator: DOH212
Where differences exist between the handbook and the SAL, the SAL should be taken as containing the correct subject offering details.

Subject information

Duration Grading System School:
One sessionHD/FLSchool of Dentistry and Health Sciences

Enrolment restrictions

Restricted to students enrolled in the Bachelor of Oral Health (Therapy/Hygiene) course.
Prerequisite(s)Incompatible subject(s)Related subject(s)
DOH112BMS291 BMS291 BMS291 subject content is embedded into DOH212

Learning Outcomes

Upon successful completion of this subject, students should:
be able to:
* define and use common pathophysiological and pharmacological terms;
* demonstrate an understanding of cellular injury and adaptation to injury;
* identify the relative contributions of genetic and environmental factors in health and disease;
* describe the involvement of microorganisms in disease;
* describe the characteristics of neoplastic cells and name and describe the mechanisms of action of the major classes of chemotherapeutic drugs;
* describe the consequences of alterations in fluids, electrolytes and acid-base balance;
* describe the four pharmacokinetic processes (absorption, distribution, metabolism and elimination);
* outline key pharmacodynamic principles (eg agonist and antagonists, receptor-drug interactions);
* name and describe the actions of the major classes of antimicrobial drugs;
* outline the major haematological pathologies and malignancies;
* describe the pathogenesis of major cardiovascular system, respiratory system and musculoskeletal system dysfunction;
* describe the aetiology and manifestations of shock;
* describe the major types of musculoskeletal pathology including both mechanical and physiological injuries;
* outline the primary pharmacological interventions used in the treatment of cardiovascular, respiratory and musculoskeletal disease;
* demonstrate an understanding of the origin and main theories of pain and the pharmacological management of pain;
* decribe the pathogenesis and pharmacological treatment of inflammation;
* describe and identify the common anomalies and developmental abnormalities of teeth;
* describe the aetiology, pathogenesis and microscopic features of dental caries and inflammatory periodontal disease;
* describe and identify infectious and reactive conditions and lesions of the oral soft tissues.

Syllabus

The subject will cover the following topics:
* Cell injury, adaptation and death * Pharmacokinetics and pharmacodynamics * Fluid, electrolyte and acid-base imbalances * Pain and analgesic agents * Inflammation and anti-inflammatory agents * Infectious disease and antimicrobial agents * Neoplastic disorders and antineoplastic agents * Cardiovascular dysfunction (coagulopathy, hypertension, atherosclerosis, dysrhythmias, pump failure) and associated pharmacology * Respiratory dysfunction (asthma, chronic airways limitation, hypoventilation, pulmonary hypertension) and associated pharmacology * Musculoskeletal dysfunction (arthritis, osteoporosis, metabolic disorders, muscular dystrophy) and associated pharmacology * Dental caries and inflammatory periodontal disease * Developmental abnormalities of the dentition * Infectious oral conditions * Non-infectious inflammatory conditions of the oral mucosa * Reactive pathology of the oral mucosa

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The information contained in the 2015 CSU Handbook was accurate at the date of publication: 01 October 2015. The University reserves the right to vary the information at any time without notice.